Researchers Cecilia Algarín,Charles Nelson, Patricio Peirano, Alissa Westerlund, Sussanne Reyes and Betsy Lozoff report in the Developmental Medicine & Child Neurology journal issue of May, 2013 on the assessment of the effects of iron-deficiency anemia (IDA) in infancy on executive functioning at age 10 years, specifically inhibitory control on the Go/No-Go task. Results indicated that IDA in infancy was associated with slower reaction times and poorer inhibitory control 8 to 9 years after iron therapy. These findings are consistent with the long-lasting effects of early IDA on myelination and/or prefrontal–striatal circuits where dopamine is the major neurotransmitter.
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