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Iron-deficiency anemia in infancy and poorer cognitive inhibitory control at age 10 years

Researchers Cecilia Algarín,Charles Nelson, Patricio Peirano, Alissa Westerlund, Sussanne Reyes and Betsy Lozoff report in the Developmental Medicine & Child Neurology journal issue of  May, 2013 on the assessment of the effects of iron-deficiency anemia (IDA) in infancy on executive functioning at age 10 years, specifically inhibitory control on the Go/No-Go task. Results indicated that IDA in infancy was associated with slower reaction times and poorer inhibitory control 8 to 9 years after iron therapy. These findings are consistent with the long-lasting effects of early IDA on myelination and/or prefrontal–striatal circuits where dopamine is the major neurotransmitter.